Medical Marijuana

Human Cannabinoid Pharmacokinetics

A multitude of roles for the endogenous cannabinoid system has been proposed by recent research efforts. A large number of endogenous cannabinoid neurotransmitters or endocannabinoids have been identified, and the CB-1 and CB-2 cannabinoid receptors have been characterized. The presence of other receptors, transporters, and enzymes responsible for the synthesis or metabolism of endocannabinoids are […]

  ABSTRACT:Background We consider how many cannabis users may need to be prevented in order to prevent one case ofschizophrenia or psychosis [defined as number needed to prevent (NNP)]. Method Calculation for England and Walesusing best available estimates of: incidence of schizophrenia; rates of heavy and light cannabis use; and risk thatcannabis causes schizophrenia. Results […]