Conservative Therapies

Hashibe M1, Morgenstern H, Cui Y, Tashkin DP, Zhang ZF, Cozen W, Mack TM, Greenland S. Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1829-34. Abstract BACKGROUND: Despite several lines of evidence suggesting the biological plausibility of marijuana being carcinogenic, epidemiologic findings are inconsistent. We conducted a population-based case-control study of the association between marijuana use and the risk of lung and upper aerodigestive tract cancers in Los […]

Human Cannabinoid Pharmacokinetics

A multitude of roles for the endogenous cannabinoid system has been proposed by recent research efforts. A large number of endogenous cannabinoid neurotransmitters or endocannabinoids have been identified, and the CB-1 and CB-2 cannabinoid receptors have been characterized. The presence of other receptors, transporters, and enzymes responsible for the synthesis or metabolism of endocannabinoids are […]

  ABSTRACT:Background We consider how many cannabis users may need to be prevented in order to prevent one case ofschizophrenia or psychosis [defined as number needed to prevent (NNP)]. Method Calculation for England and Walesusing best available estimates of: incidence of schizophrenia; rates of heavy and light cannabis use; and risk thatcannabis causes schizophrenia. Results […]